Franco Locatelli Selected Research

treosulfan

3/2022	Busulfan-fludarabine- or treosulfan-fludarabine-based myeloablative conditioning for children with thalassemia major.
1/2022	Impact of Treosulfan Exposure on Early and Long-Term Clinical Outcomes in Pediatric Allogeneic Hematopoietic Stem Cell Transplantation Recipients: A Prospective Multicenter Study.
1/2021	Total Body Irradiation or Chemotherapy Conditioning in Childhood ALL: A Multinational, Randomized, Noninferiority Phase III Study.
10/2020	Treosulfan-fludarabine-thiotepa-based conditioning treatment before allogeneic hematopoietic stem cell transplantation for pediatric patients with hematological malignancies.
12/2017	High interpatient variability of treosulfan exposure is associated with early toxicity in paediatric HSCT: a prospective multicentre study.
6/2015	Treosulfan-based conditioning regimen for allogeneic haematopoietic stem cell transplantation in children with sickle cell disease.
7/2012	Allogeneic hematopoietic stem cell transplantation in thalassemia major: results of a reduced-toxicity conditioning regimen based on the use of treosulfan.

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Franco Locatelli Research Topics

Disease

128	Neoplasms (Cancer) 10/2022 - 05/2002
77	Leukemia 01/2022 - 10/2002
65	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2022 - 07/2002
54	Graft vs Host Disease (Graft-Versus-Host Disease) 10/2022 - 05/2002
35	Infections 10/2022 - 12/2002
31	Hematologic Neoplasms (Hematological Malignancy) 01/2022 - 05/2002
26	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 11/2021 - 02/2003
19	Neuroblastoma 01/2021 - 06/2008
16	beta-Thalassemia (Cooley's Anemia) 03/2022 - 06/2002
16	COVID-19 01/2022 - 01/2020
15	Residual Neoplasm 05/2022 - 11/2003
15	Thalassemia 01/2022 - 06/2002
12	Bronchiolitis Obliterans Syndrome 10/2021 - 08/2002
12	Juvenile Myelomonocytic Leukemia 01/2021 - 04/2004
11	Hemophagocytic Lymphohistiocytosis (Hemophagocytic Syndrome) 01/2022 - 06/2005
10	Aplastic Anemia (Anemia, Hypoplastic) 01/2021 - 09/2004
8	Glioma (Gliomas) 06/2022 - 01/2005
8	Disease Progression 06/2022 - 05/2002
8	Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune) 01/2022 - 04/2003
8	Lymphoma (Lymphomas) 01/2022 - 09/2004
8	Inflammation (Inflammations) 11/2021 - 06/2007
8	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 11/2021 - 06/2002
8	Lymphoproliferative Disorders (Lymphoproliferative Disorder) 01/2019 - 04/2002
8	Cytomegalovirus Infections (Inclusion Disease) 10/2018 - 04/2005
8	Acute Promyelocytic Leukemia 01/2018 - 01/2004
7	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 01/2022 - 04/2012
7	Fanconi Anemia (Fanconi's Anemia) 01/2021 - 09/2007
7	Sickle Cell Anemia (Hemoglobin S Disease) 12/2019 - 03/2003
7	Sarcoma (Soft Tissue Sarcoma) 04/2016 - 06/2006
6	Cytokine Release Syndrome 01/2022 - 01/2019
6	Hodgkin Disease (Hodgkin's Disease) 01/2022 - 01/2016
6	Medulloblastoma 01/2021 - 01/2016
5	Bone Marrow Failure Disorders 11/2022 - 09/2007
5	Rhabdomyosarcoma 10/2021 - 09/2011
5	Glioblastoma (Glioblastoma Multiforme) 01/2021 - 01/2015
5	Neutropenia 07/2019 - 12/2002
5	Virus Diseases (Viral Diseases) 01/2019 - 02/2000
5	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2017 - 08/2003
4	Primary Immunodeficiency Diseases 10/2022 - 01/2017
4	Diffuse Intrinsic Pontine Glioma 01/2022 - 05/2017
4	Brain Neoplasms (Brain Tumor) 01/2022 - 07/2013
4	Autoimmune Diseases (Autoimmune Disease) 01/2022 - 09/2009
4	Hemorrhage 12/2021 - 07/2005
4	Cytopenia 01/2021 - 04/2014
4	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/2021 - 06/2005
4	Thrombocytopenia (Thrombopenia) 01/2021 - 03/2011

Drug/Important Bio-Agent (IBA)

23	Proteins (Proteins, Gene)FDA Link 12/2021 - 08/2005
23	Biological ProductsIBA 11/2021 - 11/2003
22	Pharmaceutical PreparationsIBA 12/2022 - 03/2006
19	LigandsIBA 01/2021 - 08/2003
16	blinatumomabIBA 01/2022 - 12/2016
16	AntigensIBA 01/2021 - 02/2000
14	Biomarkers (Surrogate Marker)IBA 06/2022 - 04/2005
14	CytokinesIBA 11/2021 - 06/2007
12	fludarabineIBA 03/2022 - 11/2002
12	MicroRNAs (MicroRNA)IBA 01/2019 - 09/2011
10	SteroidsIBA 10/2022 - 01/2007
10	AntibodiesIBA 01/2022 - 07/2009
10	Chimeric Antigen ReceptorsIBA 01/2022 - 12/2013
10	Monoclonal AntibodiesIBA 01/2021 - 02/2002
9	HLA Antigens (Human Leukocyte Antigens)IBA 01/2021 - 08/2008
8	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 04/2002
8	Cyclosporine (Ciclosporin)FDA LinkGeneric 01/2020 - 05/2002
7	treosulfanIBA 03/2022 - 07/2012
7	Antiviral Agents (Antivirals)IBA 01/2021 - 06/2003
7	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2021 - 01/2006
7	EnzymesIBA 01/2019 - 02/2012
7	KIR ReceptorsIBA 01/2016 - 03/2009
6	Immunoglobulins (Immunoglobulin)IBA 05/2022 - 04/2008
6	VaccinesIBA 01/2022 - 10/2013
6	Inosine Triphosphate (ITP)IBA 01/2022 - 04/2003
6	InterferonsIBA 01/2021 - 10/2004
6	Antilymphocyte Serum (Anti-Thymocyte Globulin)IBA 01/2020 - 08/2003
6	Rituximab (Mabthera)FDA Link 01/2020 - 02/2002
6	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/2020 - 06/2002
6	Prednisone (Sone)FDA LinkGeneric 02/2016 - 07/2002
5	T-Cell Antigen Receptors (T-Cell Receptor)IBA 05/2022 - 01/2016
5	Busulfan (Busulfex)FDA Link 03/2022 - 02/2014
5	Messenger RNA (mRNA)IBA 01/2022 - 06/2003
5	Imatinib Mesylate (Gleevec)FDA Link 01/2021 - 03/2006
5	Tretinoin (Retinoic Acid)FDA LinkGeneric 01/2021 - 01/2004
4	Neoplasm Antigens (Tumor Antigens)IBA 01/2022 - 05/2004
4	dipinacoline glutamateIBA 01/2022 - 05/2017
4	eltrombopag FDA Link 01/2022 - 01/2015
4	Therapeutic UsesIBA 01/2022 - 01/2014
4	BNT162 VaccineIBA 01/2022 - 10/2021
4	Cytarabine (Cytosar-U)FDA LinkGeneric 11/2021 - 08/2008
4	Immunoglobulin G (IgG)IBA 11/2021 - 10/2013
4	ruxolitinibIBA 10/2021 - 09/2016
4	Etoposide (VP 16)FDA LinkGeneric 01/2021 - 03/2011

Therapy/Procedure

119	Therapeutics 01/2022 - 04/2002
115	Hematopoietic Stem Cell Transplantation 01/2022 - 05/2002
77	Transplantation 11/2022 - 05/2002
43	Drug Therapy (Chemotherapy) 01/2022 - 10/2002
37	Stem Cell Transplantation 12/2021 - 05/2002
25	Immunotherapy 01/2022 - 03/2011
15	Bone Marrow Transplantation (Transplantation, Bone Marrow) 10/2013 - 06/2002
6	Cell Transplantation 01/2020 - 03/2009
5	Cell- and Tissue-Based Therapy (Cell Therapy) 01/2022 - 12/2005
4	Radiotherapy 01/2022 - 01/2005